Intra Articular Injection

Intra Articular Knee Injection

Knee osteoarthritis (OA), is a degenerative joint disease, typically the result of wear and tear and progressive loss of articular cartilage. OA is common in elderly persons and a major cause for disability. The intensity of the clinical symptoms may vary with everyone, but it typically becomes more severe and debilitating over time. The rate of severity and progression varies for each individual, and so their clinical symptoms and knee pain. The prevalence of knee OA will continue to increase as life expectancy, and obesity rises. Studies have found that the majority of the OA patients were asymptomatic, although with radiographic findings.



  • Occupation – prolonged standing and repetitive knee bending
  • Weight
  • Health – metabolic syndrome
  • Muscle weakness or imbalance
  • Articular trauma


  • Age
  • Genetics
  • Gender – females more common than males
  • Race



Approach to ultimately surgical treatment options. Intra-articular (IA) treatment for osteoarthritis (OA) is a non-surgical treatment option. This non-surgical intervention does not alter the underlying disease process but may substantially diminish pain and disability. Intra-articular injections may be useful for symptomatic knee osteoarthritis, especially where there is a considerable inflammatory component. The different intraarticular injection is corticosteroids, viscosupplements and blood-derived products.

The delivery of the corticosteroid directly into the knee may reduce local inflammation associated with osteoarthritis and minimize the systemic effects of the steroid. Whereas the other injectable option, the hyaluronic acid (HA) injections is a glycosaminoglycan that is found throughout the human body and is an important component of synovial fluid and articular cartilage. HA injection into the joint acts as a lubricant and may help to increase the natural production of HA in the joint.

Osteoarthritis is the most common type of arthritis, and generally, the chances of developing osteoarthritis rises after age 45 with the knee being one of the most affected areas. The most common cause of osteoarthritis of the knee is age, and Malaysia is fast developing into an ageing society. InfoMed sat down with Dr Ang Hock Leong, Consultant Orthopedic and Joint Replacement Surgeon, Columbia Asia Hospital – Klang to understand the medical options available for the treatment of osteoarthritis, precisely the non-surgical option.


  • Worsening overtime
  • Worse with prolonged activity
  • Worse with inactivity
  • Worse with repetitive bending or stairs
  • Better with rest
  • Better with ice or anti-inflammatory medication
  • Knee stiffness
  • Knee swelling
  • Decreased ambulatory (walkabout) capacity

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